I’m too wordy and I know this. I will try to break up the text wall with pics. Captions will be underneath pics, if I can figure out imgur again (it's been a while!)
The Fractal Design Meshify 3XL, in non-RGB black with glass wall. It's roomy and I'm familiar with Fractal and it's mostly good. I prefer all natural rainbows over LED ones, mostly. Mostly.
Okay, this is maybe underspray? As in when they painted this part they didn't successfully paint it entirely. It's hard to photograph, but I can see this from outside the case in proper lighting. Not a huge problem but this is a premium case and this is the sort of fit and finish issue I don't expect from Fractal Design. This is the metal cover that hides the openings one would use to route power supply cables to the motherboard.
Okay so this is the floor of the case, after I've removed the back side panel, the inside plastic side panel, and the floor "ramp" panel (that would guide air from front fans up and into an air cooled GPU). This appears to fit the 120mm fan mount I bought but never used for my EKWB D5 pump in 2018. I didn't take a picture, but the pump mount bracket DOES fit when the ramp panel is in place. The
Lophroaig shaped case holes are where the plastic airguide ramp piece slots in (it's also held down by the plastic side panel and maybe requires inconvenient PC parts disassembly to remove after the fact). Like I'd probably need to pull the GPU to get the cable shroud off then the plastic side panel then the ramp. I plan to not use the side plastic though.
Also please note (above pic) the lower 120mm fan bracket that's attached in the middle of the 140mm 3-fan cutouts in this photo. The screws protrude a bit and I have no need for 120mm fans in this build, so I removed those and they're going into the parts bin. Unlike the cable shroud (which I can see from outside the case), this hidden away part was perfectly painted. Just saying.
Okay, so this is great access to the power supply, but as I noted before this is normally covered by an airflow ramp shroud, which isn't removable unless the inside plastic side panel is also removed, and possibly also the partly painted metal cable management shroud which might touch a GPU backplate. This is a thoughtful case design, but not flawless. The case is complex, and playing paper dolls (putting components into case prior to affixing them and assembling properly) is probably a must. I struggled later on playing with the power supply with the ramp shroud in place, though you have good access from behind the mobo wallfloor. You can pull the power supply out the back of the case, but cables are never long enough to permit careful seating like that. Especially not the high power GPU cable. I struggled with the power supply connections in this case despite thoughtful design and wide open looking spaces. I also don't build often so maybe partly a "skill issue".
Okay so super open, perhaps to the point of being less rigid. This case felt quite solid to me at all times though. It's a great looking and open design despite some small flaws to pick at.
Okay,
@N00balicious there is no angling, and no overhanging PC gut here. It fits and it's great. I might prefer 90 degree angled Displayport cables or adapters but that would also mean I could put the case closer to wall, making the poor Noctua exhaust fan tired. (this is my old CPU/mobo with new power supply in new Meshify 3XL case. A day after this was taken I added in the PNY RTX5080 GPU AND my RGB magnetic lightstrip.
Measure twice, cut thrice? Also it hurts to see what flipping my Nano S around did to my nice Ikea pleather desktop surface. This card is huge (three slots wide and 329mm long (longer than the meshify 3XL's soft max length when putting a side radiator into the case). A quick eyeball suggests that it might fit anyway. Maybe with a hammer.
You can see the GPU encroaches onto the installed plastic side panel ever so slightly (maybe 5mmish). You can see the underpainted metal cable shroud sorta touching the GPU backplate. Note that this GPU is super short when shorn of its OEM cooler, but I still worry that the Alphacool backplate I have will still engage in inappropriate unwanted contact with that problematic partly painted shroud piece. Also I had zero intention of properly managing my cables with this strictly temp build.
Yet with these surprisingly helpful clips, despite not wanting to I still found my cables being super nicely managed. Bravo on these back cable clips!
Okay.
@steelghost is egging me on with regard to enbiggening the front radiator. How dare they! Noctua fan pairs aren't cheap!

You can see roughly 2 inches (~5cm) distance from the fan to the beginning of the plastic side wall... a 60mm thick push-pulled front rad might encroach on a side radiator but not entirely sure. It probably also encroaches on the floor 120mm pump mount holes. Side note - WHY do pump mounts only happen in the center, when it would be better to recess them back to give extra room in front for tubing?? In my Nano S I had to abandon the provided 120mm mounting holes because of this issue. Maybe it's more of a pump design issue.
No, that 329mm GPU doesn't really encroach into the side radiator area. Not one bit! Maybe.
I think these are reflections and not marring of the GPU after I peeled the plastic stuff off of it. Not that it matters...
The new block is here! I won't have time to order in more parts and get it set up for probably a couple weeks though and also I want several days on air to ensure the GPU part isn't coil whining or not working well. ON A SIDE NOTE...this looks like a 2-slot wide cover. It's not too late to pop this into a quick 280mm rad loop in my Nano S!! I kid, I kid!
This is what I'm dealing with; my fittings are green as are interior surfaces that I can see. I think I will soak parts (including radiator) in mild detergent then flush with distilled water - I don't know if it's okay to flush with something harsher (diluted vinegar) to descale a bit, the radiator isn't plated. The nickel plated parts I'm not going to use anything other than mild elbow grease (plastic dishwashing scrubber), diluted Dawn detergent, and maybe metal polish if I need to.
I don't want to post the picture (old build) but the cracks in my 1080 block were definitely not there immediately after installation of the water block. I think there may have been flexing of the board. Given the short size of the blocked 5080 I wasn't planning to prop the board up (horizontal layout) with a brace, but should I?
Edit - THANKS and sorry my premature publish happened. THis is the end of tonight's post!
Moar edits - holy typos batman!